As of 13 May 2022, 28 Member States in four World Health Organization Regions (the Region of the Americas, the European, Eastern Mediterranean and Western Pacific Regions) have reported smallpox cases to WHO. monkey or monkeypox where monkeypox is not common or has not been previously reported.
As epidemiological investigations continue, the majority of reported cases in recently affected countries have presented through sexual health or other health services in primary or secondary care settings, with a history of travel to countries in Europe and North America instead of countries where the virus is known to be present. be.
The sudden and unexpected appearance of monkeypox simultaneously in several regions without direct and immediate travel links to regions with a long history of monkeypox suggests that there may have been undetected transmission for several weeks or more.
Description of the outbreak
As of June 8, 1,285 laboratory-confirmed cases and one probable case have been reported to WHO from 28 countries in four WHO regions where monkeypox is not common or previously reported. This represents an increase of 505 laboratory-confirmed cases since the previous outbreak information bulletin dated June 4, 2022, which reported 780 cases. As of June 8, 2022, no associated deaths have been reported in these four regions.
Of the cases reported in these regions, the majority (87%) of the confirmed cases are from the WHO European Region (1112). Confirmed cases have also been reported in the Region of the Americas (153), the Eastern Mediterranean Region (14), and the Western Pacific Region (6). The number of cases fluctuates as new information is reported and becomes available daily and data is verified in accordance with the International Health Regulations (IHR 2005).
Until now, the clinical presentation Cases of monkeypox associated with this outbreak have been variable.
- Many cases in this outbreak do not present the clinical picture classically described for monkeypox (fever, swollen lymph nodes, followed by a concentrated rash on the face and extremities).
- Atypical features described include: presentation of only a few lesions or even a single lesion; lesions that start in the genital or perineal/perianal area and do not spread further; lesions appearing at different stages of development (asynchronous); and the appearance of lesions before the appearance of swollen lymph nodes, fever, malaise or other symptoms.
Modes of transmission through sexual contact are unknown; While it is known that close physical contact can lead to transmission, it is unclear what role sexual body fluids, including semen and vaginal fluids, play in the transmission of monkeypox.
Two types of vaccines (ACAM-2000 and MVA-BN) are currently being implemented by some Member States to serve as close contact prophylaxis. Others may have stocks of other types of vaccines (eg, LC16).
Also, from the beginning of, 1,536 suspected cases have been reported in eight countries in the WHO African Region, of which 59 cases have been confirmed and 72 deaths have been reported. Continued detection of the virus and reported deaths in some countries in the African Region underscore the need to better understand the source, transmission dynamics, and provide people with the information and support they need to protect themselves and others. in a variety of different contexts. In countries with a long history of monkeypox, more evidence is needed to understand current and new sources of infection.
Source: World Health Organization (WHO)
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